Follicle Treatment, our hair loss serum treatment, a natural DHT blocker is an anti aging solution to male and female pattern hair loss. This hair loss product is based on latest medical research on causes of hair loss in women and men. It is now known that dihydrotestosterone (DHT), a by-product of testosterone, is the detrimental agent that may be a hair loss cause. Simply put, under certain conditions DHT “strangles” hair follicles. New hair loss causes research has proven that DHT is responsible for the progressive shrinking of the hair follicle. While this process is the primary cause of hair loss in women, there are several other factors that contribute to further deterioration of the hair follicle. Oxidative stress, reactive oxygen species and free radical generation may account for hair thinning and loss to a significant degree. Nutrient deficient hair follicles, poor circulation of the scalp, over active sebaceous glands, and clogged or harshly treated hair follicles are among these factors.
Hair loss in women: Given the protective effect of estrogen and progesterone, there are female hair thinning, which are due to hormonal imbalance and increased DHT level as well. DHT blockers such as Follicle Treatment enjoying natural ingredients stimulates hair growth by blocking androgen receptors and enzyme 5-alpha reductase, which in turn reduce DHT production in both men and women. Causes of hair loss in women appear to be stress related to a great extent and other anti aging approaches may be helpful.
In susceptible hair follicles, dihydrotestosterone binds to the androgen receptor, and the hormone-receptor complex activates the genes responsible for the gradual transformation of large terminal follicles to miniaturized follicles. Both young women and young men with AGA have higher levels of 5alpha reductase and androgen receptor in frontal hair follicles compared to occipital follicles. At the same time, young women have much higher levels of cytochrome p-450 aromatase in frontal follicles than men who have minimal aromatase, and women have even higher aromatase levels in occipital follicles.
DHT blockers use different mechanisms to reduce dihydrotestosterone, among them are:
Blocking the alpha receptors in the hair follicles
Inhibition of the enzyme 5 alpha reductase, responsible for conversion of testosterone into DHT
Reducing the production of DHT
Reducing the substances that can produce the enzyme 5 alpha reductase like cholesterol
Androgenic Alopecia the most common form of male and female hair shedding affects 50% of men by the age 50 and 50% of women by the age 60. Advances in biology of hair loss at molecular level provided better understanding of causes of hair loss and a new approach to its treatment. This approach involves inhibition of 5-alpha reductase, the enzyme which reduces testosterone to its more active form ,dihydro testosterone. Dihydrotestosterone is currently thought to be the most potent androgen affecting the human hair growth cycle, with adverse effects in male pattern hair loss. A recent study suggests role of interleukin-17 in androgenic alopecia and inhibition of this inflammatory maker as a potential treatment for hair loss.